Multiple meds danger
February 12, 2016
Polypharmacy, officially
described as the simultaneous use
of five or more medications, can
trigger a decline into frailty and
death, according to a report from
the Monash University.
Research, led by Monash’s Centre
for Medicine Use and Safety, in
collaboration with the University
of Sydney, followed men aged 70
years and over measuring increases
in the Drug Burden Index (DBI).
Higher DBIs were associated with
a 22% greater risk of transition
from a robust state, to various
stages of frailty, and finally death.
The work was published in the
Journal of the American Geriatrics
Society.
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