Phenylephrine letter

March 21, 2014

The Australian Self Medication Industry (ASMI) said recent information on the pharmacokinetics of phenylephrine was interesting but of “limited value.” ‘Increased Phenylephrine Plasma Levels with Administration of Acetaminophen’ was published in the New England Journal of Medicine and said three studies showed unexpected pharmacokinetic interaction between acetaminophen, ibuprofen and phenylephrine, resulting in nearly a quadrupling in maximal plasma concentration. “Halving the dose of phenylephrine that was combined with acetaminophen to 5 mg produced a plasma concentration– time curve similar to that for 10 mg of phenylephrine administered alone.” ASMI director of scientific and regulatory affairs Steve Scarff said it was important to note that the information was in letter form, not a publication of a full study. CLICK HERE for more.

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Pharmacy Daily | Phenylephrine letter

Phenylephrine letter

Other recent headlines

PD breaking news – Pharmacists to administer NIP vaccinations in aged care

PD breaking news – Top Western Australian talent honoured

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SEARCH PHARMACY DAILY

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