THE two major clinical
shortcomings of morphine use in
pain therapy, namely potentially
fatal respiratory depression
and addiction, appear to have
been overcome in a tailor-made
substitute product, the result of
novel research out of universities in
the US and Germany and published
in the journal Nature.
Dubbed PZM21, this structurally
designed product has proven
to be at least equally successful
as an analgesic but does not
cause respiratory depression nor
“reinforcing activity” on dopamine
reward centres at therapeutic levels
in mice, authors state.
Extensive further research will be
required before the drug can be
tested on humans, the paper said.The above article was sent to subscribers in Pharmacy Daily's issue from 24 Aug 16 To see the full newsletter, see the embedded issue below or CLICK HERE to download Pharmacy Daily from 24 Aug 16
RESPONDING to the findings from the Royal Commission into Aged Care Quality and Safety, a recent government initiative aims to improve medication management in residential aged care facilities by introducing on-site pharmacists.
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