Goodbye to PMS?
October 19, 2012
PMS may be getting its marching
orders soon, after a study
published in Phytomedicine found
that an extract of the herb vitex
agnus-castus (available under the
brand name Premular) is the most
effective dosage and preferred
option to relieve the symptoms of
premenstrual syndrome in women.
The multicentre, double-blind,
placebo-controlled, parallel-group
study included 162 females with
PMS aged between 18 and 45 years.
During the study participants were
randomised to either placebo or
different doses of Premular over three
menstrual cycles, with symptom
severity assessed for irritability,
mood alteration, anger, headache,
bloating and breast fullness.
Study results showed improvements
for the group on the normal dosage
of Premular was superior in the
reduction of all six individual
symptom scores, compared to the
placebo and smaller dosage groups.
Interestingly, a higher dose
demonstrated no significant
difference in reducing symptom
severity compared to the normal
Premular dose.
Overall after treatment with the
normal Premular dose, 49% of all
patients had no symptoms and 31%
had mild symptoms.
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